Two-dimensional Speckle -Tracking Echocardiography derived longitudinal strain in patients with Unstable angina and normal left ventricular ejection fraction

Longitudinal strain (LS) measurements by Speckle Tracking Echocardiography (STE) is a point of care imaging modality that had been documented to have role in NSTEMI/STEMI and stable Coronary artery disease (CAD). This study aims determine the accuracy LS parameters diagnosis predicting severity CAD unstable angina patients with no regional wall motion abnormalities. It was prospective analytical which 143 low-risk Unstable underwent STE. Based on angiogram results, participants were divided into obstructive control group. Patients (n ¼ 79) significantly higher GLS Trans GLS12 (¡18.2 ± 3.5% Vs ¡20.4 3.2%, p 0.001 ¡16.0 ¡18.1 3.0, respectively) compared normal/non-obstructive coronaries 45). Both trans independent predictors multivariate logistic regression. However, diagnostic (AUC 0.683) 0.687) only modest. But positive predictive value grossly altered >-16.1% high (92.1%). Regional longitudinal (RLS) noted be group one (RLSLAD: ¡18.8 4.8 ¡21.2 4.5, 0.007; RLSLCX: ¡18.6 3.5, 0.001; RLSRCA: 3.6 ¡20.2 3.4, 0.031). Diagnostic UA subgroup >16.1% probability having particular multivessel hence these can subjected CAG without further ischemic testing.